| # | Equipo | Pts | PJ | G | E | P | DG | Forma |
|---|---|---|---|---|---|---|---|---|
| 1 | Vancouver Whitec | 49 | 25 | 15 | 4 | 6 | +33 | GPGPG |
| 2 | Houston Dynamo | 44 | 26 | 13 | 5 | 8 | +4 | EPGEE |
| 3 | St. Louis City | 44 | 26 | 12 | 8 | 6 | +9 | GGEGE |
| 4 | FC Dallas | 44 | 26 | 12 | 8 | 6 | +7 | EGGGE |
| 5 | San Jose Earthqu | 42 | 26 | 12 | 6 | 8 | +8 | EGGEE |
| 6 | Los Angeles FC | 41 | 27 | 11 | 8 | 8 | +14 | EPGEE |
| 7 | Colorado Rapids | 36 | 26 | 11 | 3 | 12 | +1 | EGEPG |
| 8 | Los Angeles Gala | 33 | 27 | 8 | 9 | 10 | -8 | GEPGP |
| 9 | Portland Timbers | 32 | 26 | 9 | 5 | 12 | -1 | PPEGP |
| 10 | Seattle Sounders | 32 | 25 | 8 | 8 | 9 | -3 | GEEEE |
| 11 | San Diego | 31 | 26 | 8 | 7 | 11 | 0 | EPPPG |
| 12 | Austin | 30 | 26 | 7 | 9 | 10 | -12 | EGEEG |
| 13 | Real Salt Lake | 29 | 26 | 8 | 5 | 13 | -7 | PPPPE |
| 14 | Minnesota United | 29 | 26 | 7 | 8 | 11 | -7 | PPPPE |
| 15 | Sporting Kansas | 18 | 25 | 5 | 3 | 17 | -34 | PGPPP |
| 1 | Nashville SC | 57 | 26 | 17 | 6 | 3 | +32 | GEPEG |
| 2 | New England Revo | 46 | 26 | 14 | 4 | 8 | +12 | GGGPG |
| 3 | Inter Miami | 46 | 26 | 12 | 10 | 4 | +15 | EEEEG |
| 4 | Charlotte | 43 | 26 | 12 | 7 | 7 | +10 | GEGEG |
| 5 | Chicago Fire | 39 | 25 | 11 | 6 | 8 | +7 | PPEEE |
| 6 | Philadelphia Uni | 36 | 26 | 10 | 6 | 10 | +8 | GGGGG |
| 7 | Orlando City SC | 34 | 26 | 10 | 4 | 12 | -14 | PGGGE |
| 8 | New York Red Bul | 33 | 26 | 9 | 6 | 11 | -14 | GGPEP |
| 9 | FC Cincinnati | 33 | 25 | 8 | 9 | 8 | -7 | EEPPE |
| 10 | New York City FC | 32 | 26 | 8 | 8 | 10 | +5 | PGPEE |
| 11 | DC United | 29 | 25 | 6 | 11 | 8 | -8 | PEGEP |
| 12 | Toronto FC | 29 | 26 | 6 | 11 | 9 | -10 | PPGEE |
| 13 | Columbus Crew | 26 | 26 | 7 | 5 | 14 | -5 | GPPGP |
| 14 | Atlanta United F | 26 | 26 | 7 | 5 | 14 | -13 | GEPEP |
| 15 | CF Montreal | 21 | 26 | 5 | 6 | 15 | -22 | PPPPP |
